The Journal of Phytopharmacology 2023; 12(1):39-43 ; DOI:10.31254/phyto.2023.12106
Evaluation of in vitro antibacterial activity of Carum copticum extract against drug resistant Staphylococcus aureus from clinical and food sources
Javed Ahamad Khan1 , Ram Swaroop Rathore2 , Iqbal Ahmad3 , Rubina Gill4 , Fohad Mabood Husain5 , Javeed Akhtar6 , Leta Deressa Tolesa7 , Misbahu Abdu Ayanso8 , Mekonnen Begna9
1. Department of Natural Resource Management, Bedele Campus, Mattu University, Bedele-P.O. Box-318, Ethiopia & Division of Veterinary Public Health, Indian Veterinary Research Institute, Bareilly-243122, India & Department of Agricultural Microbiology, Faculty of Agricultural Sciences, Aligarh Muslim University, Aligarh-202002, India
2. Division of Veterinary Public Health, Indian Veterinary Research Institute, Bareilly-243122, India
3. Department of Agricultural Microbiology, Faculty of Agricultural Sciences, Aligarh Muslim University, Aligarh-202002, India
4. School of Agriculture, Lovely Professional University, Phagwara-144001, India
5. Department of Food Science and Nutrition, King Saud University, Riyadh-12372, Saudi Arabia
6. Department of Chemical Engineering, Adigrat University, P.O.Box-50, Adigrat, Tigray, Ethiopia
7. Department of Chemistry, Mattu University, Mettu, P.O. Box-318, Ethiopia
8. Department of Plant Science, Bedele Campus, Mattu University, Bedele, Ethiopia
9. Department of Natural Resource Management, Bedele Campus, Mattu University, Bedele- P.O. Box-318, Ethiopia
*Author to whom correspondence should be addressed.
Received: 17th August, 2022 / Accepted: 19th January, 2023
Staphylococcus aureus is commensal and human pathogen both. The bacterium is one of the mostcommon causes of food borne infections also in all over the world. C. copticum (Ajwain) is an aromaticspice used as a medicinal plant from ancient time for treating different human diseases includinginfectious diseases. The highest anti-staphylococcal activity in terms of inhibition zone was recorded18.5 mm whereas 14.5 mm as lowest. The MIC range of ethanolic extract was evaluated amid 1.56mg/ml to 3.12 mg/ml. The C. copticum (seed) extract might be useful as anti-staphylococcal agent aswell as natural food preservative.
Carum copticum, Drug resistance, Natural products, Anti-staphylococcal Activity; Minimum Inhibitory Concentration (MIC)
HOW TO CITE THIS ARTICLE
Khan JA, Rathore RS, Ahmad I, Gill R, Husain FM, Akhtar J, Tolesa LD,Ayanso MA, Begna M. Evaluation of in vitro antibacterial activity ofCarum copticum extract against drug resistant Staphylococcus aureusfrom clinical and food sources. J Phytopharmacol 2023; 12(1):39-43. doi:10.31254/phyto.2023.12106
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